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Haematology

Clinical Studies

The Clinical Trial Unitconducted a record number of clinical trials, many of them part of national and international collaborative studies.  In particular, the group are involved in exciting studies involving novel therapies in the treatment of chronic myeloid leukaemia, multiple myeloma and myelodysplastic syndromes.

Actively recruiting:

Acute Myeloid Leukaemia

  • AML Decitabine
  • AML M12
  • AML M13
  • APML4

Chronic Myeloid Leukaemia

  • CML7 – Glivec with Pegylated Interferon
  • CML8 – Cessation of Glivec
  • CML TOPS - 400 vs 800mg Glivec
  • CML ALL1
  • CML ALL AMN107 – Nilotinib
  • Glivec INDY-CML and other diseases thought to be responsive to a tyrosine kinase inhibitor

Myeloma

  • MM1195 DT-PACE
  • MM Denosemab
  • MM Velcade BIR
  • Mucositis WHEY

Lymphoma

  • HD04
  • NHL 11-Hyper C-VAD
  • NHL 13 - CORAL
  • NHL – Prima
  • NHL – Velcade

Transplant

  • Transplant – Double Cord
  • Transplant – Mesenchymal Stem Cells
  • MBL polymorphism

Haemostasis

  • VWD Biostate

Ongoing but closed to recruitment:

Acute Myeloid Leukaemia

  • AML M11
  • APML3 ATRA

Chronic Lymphocytic Leukaemia

  • CLL2

Chronic Myeloid Leukaemia

  • CML4
  • CML5
  • CML6
  • BMS 006
  • BMS 013
  • BMS 034
  • BMS 035
  • CML IRIS

Iron Overload

Myeloma

  • MM6
  • MM Velcade/Doxil
  • MM Vista

Lymphoma

  • HD3
  • NHL Follicular, EBMT
  • NHL LOW4
  • NHL Mantle Cell, LY05

Transplant

  • ALLO Valacyclovir